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J J Holst Selected Research

Glucagon-Like Peptide 1 (GLP 1)

12/2019Glucagon-like peptide 1 (GLP-1).
1/2018Incretin responses to oral glucose and mixed meal tests and changes in fasting glucose levels during 7 years of follow-up: The Hoorn Meal Study.
1/2018Impact of weight loss achieved through a multidisciplinary intervention on appetite in patients with severe obesity.
6/2017Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men.
11/2016Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery.
1/2016Effect of chenodeoxycholic acid and the bile acid sequestrant colesevelam on glucagon-like peptide-1 secretion.
1/2016Short-term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial.
11/2015Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes.
1/2015Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors.
5/2014Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus.
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J J Holst Research Topics

Disease

83Type 2 Diabetes Mellitus (MODY)
01/2020 - 01/2000
30Insulin Resistance
12/2017 - 02/2001
26Obesity
12/2019 - 02/2001
25Body Weight (Weight, Body)
01/2018 - 01/2000
22Weight Loss (Weight Reduction)
10/2018 - 06/2001
17Glucose Intolerance
12/2014 - 09/2000
9Type 1 Diabetes Mellitus (Autoimmune Diabetes)
04/2016 - 02/2000
8Hypoglycemia (Reactive Hypoglycemia)
05/2012 - 01/2000
6Weight Gain
06/2017 - 08/2008
6Hyperglycemia
02/2014 - 06/2000
6Diabetes Mellitus
03/2011 - 01/2000
5Overweight
01/2017 - 09/2001
4Morbid Obesity
01/2018 - 05/2009
4Cardiovascular Diseases (Cardiovascular Disease)
12/2017 - 02/2001
4Hyperinsulinism (Hyperinsulinemia)
02/2014 - 11/2000
4Short Bowel Syndrome
06/2013 - 01/2009
3Metabolic Syndrome (Dysmetabolic Syndrome X)
06/2017 - 01/2014
3Diarrhea
03/2017 - 06/2013
3Hyperlipidemias (Hyperlipidemia)
07/2012 - 02/2001
3Chronic Pancreatitis
09/2010 - 01/2000
2Psoriasis (Pustulosis Palmaris et Plantaris)
11/2016 - 12/2015
2Gestational Diabetes (Gestational Diabetes Mellitus)
08/2013 - 09/2005
2Metabolic Diseases (Metabolic Disease)
12/2012 - 10/2012
2Heart Failure
05/2012 - 03/2011
2Gastroparesis
06/2010 - 09/2006
2Hyperplasia
11/2005 - 02/2003
2Dumping Syndrome (Syndrome, Dumping)
11/2005 - 09/2001
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2019
1Inflammation (Inflammations)
12/2019
1Liver Diseases (Liver Disease)
05/2016

Drug/Important Bio-Agent (IBA)

76Glucose (Dextrose)FDA LinkGeneric
01/2020 - 03/2000
71Glucagon-Like Peptide 1 (GLP 1)IBA
12/2019 - 01/2000
46Insulin (Novolin)FDA Link
01/2018 - 01/2000
37IncretinsIBA
01/2020 - 05/2000
34Hormones (Hormone)IBA
01/2020 - 01/2000
29Glucagon (Glukagon)FDA Link
05/2016 - 01/2000
18Peptides (Polypeptides)IBA
01/2020 - 03/2000
10LipidsIBA
12/2017 - 07/2005
8LiraglutideFDA Link
12/2017 - 08/2009
8Blood Glucose (Blood Sugar)IBA
10/2015 - 01/2000
7Glucagon-Like Peptides (Enteroglucagon)IBA
06/2017 - 01/2000
6C-PeptideIBA
01/2020 - 08/2001
6Glucagon-Like Peptide-1 Receptor AgonistsIBA
12/2019 - 02/2006
6Triglycerides (Triacylglycerol)IBA
12/2017 - 02/2001
5GhrelinIBA
01/2018 - 09/2006
5Peptide YYIBA
01/2018 - 02/2007
5Glucagon-Like Peptide-1 ReceptorIBA
01/2017 - 04/2006
5Nonesterified Fatty Acids (NEFA)IBA
05/2016 - 06/2001
5LeptinIBA
05/2015 - 12/2000
5AmidesIBA
05/2014 - 04/2000
4Gastrointestinal Hormones (Hormones, Gastrointestinal)IBA
02/2016 - 05/2009
4Exenatide (Byetta)FDA Link
09/2013 - 04/2006
4Glucagon-Like Peptide 2IBA
06/2013 - 08/2004
4Gastric Inhibitory Polypeptide (Glucose Dependent Insulinotropic Peptide)IBA
12/2007 - 11/2001
3CarbohydratesIBA
04/2016 - 02/2001
3Sitagliptin Phosphate (Januvia)FDA Link
06/2015 - 04/2010
3Metformin (Glucophage)FDA LinkGeneric
05/2014 - 04/2001
3Transcription Factors (Transcription Factor)IBA
01/2013 - 12/2007
3Proteins (Proteins, Gene)FDA Link
06/2012 - 09/2011
3Proglucagon (Glucagon Precursors)IBA
10/2011 - 06/2001
3AdiponectinIBA
12/2007 - 06/2005
3Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
09/2002 - 07/2000
2Sucrose (Saccharose)IBA
10/2015 - 02/2001
2Growth Hormone (Somatotropin)IBA
06/2015 - 07/2000
2arabinoxylanIBA
05/2014 - 01/2014
2GW002 peptideIBA
05/2014 - 03/2004
2Volatile Fatty AcidsIBA
05/2014 - 05/2014
2Dietary ProteinsIBA
07/2012 - 02/2010
2Pharmaceutical PreparationsIBA
07/2012 - 08/2011
2Dexamethasone (Maxidex)FDA LinkGeneric
05/2012 - 02/2007
2SteroidsIBA
05/2012 - 07/2010
2OxyntomodulinIBA
11/2011 - 07/2011
2Dipeptidyl-Peptidase IV InhibitorsIBA
04/2010 - 08/2005
2VildagliptinIBA
10/2008 - 08/2005
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2006 - 07/2005
2Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA
02/2006 - 09/2000
2Islet Amyloid PolypeptideIBA
09/2002 - 11/2000
2Peptide Hormones (Polypeptide Hormones)IBA
06/2001 - 12/2000
1Neuroprotective AgentsIBA
12/2019
1Cholecystokinin (Pancreozymin)IBA
01/2018
1VLDL LipoproteinsIBA
12/2017
1CholesterolIBA
12/2017
1LDL Lipoproteins (beta Lipoproteins)IBA
12/2017
1Apolipoproteins B (ApoB)IBA
12/2017
1ApolipoproteinsIBA
12/2017
1FructoseIBA
06/2017
1Lactulose (Duphalac)FDA LinkGeneric
03/2017
1Mannitol (Osmitrol)FDA LinkGeneric
03/2017
1Blood Proteins (Serum Proteins)IBA
03/2017
1Glycerol (Glycerine)FDA LinkGeneric
05/2016

Therapy/Procedure

13Gastric Bypass (Roux-en-Y Gastric Bypass)
10/2018 - 11/2005
8Therapeutics
10/2015 - 02/2001
3Subcutaneous Infusions
05/2014 - 03/2004
3Glycemic Control
07/2012 - 04/2000
2Caloric Restriction
12/2017 - 05/2015
2Injections
06/2013 - 07/2011
2Aftercare (After-Treatment)
05/2012 - 03/2001
2Intravenous Administration
10/2011 - 02/2007
2Subcutaneous Injections
03/2004 - 02/2001
1Drug Therapy (Chemotherapy)
12/2019